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Phasing-out Desflurane cover image

Phasing-out Desflurane

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MitigationScope 1🏥Anaesthesia
Game ChangerGame Changer (>100 tCO₂e per hospital or >3 tCO₂e per primary practice)
Climate Impact
500+ tCO₂e
Absolute GHG Reduction
🛢️ Equivalent to at least 1,145 barrels of oil per year for every 300-bed hospital
Local Impact56,000+ tCO₂e/yr
National Impact153,000+ tCO₂e/yr
Financial Impact
ImplicationsHigh Saving (Over $100,000)
SavingsCA$115,000
MethodologyFirst Year
ROIImmediate
Implementation Feasibility
Investment
Low
Team Size
Small but mighty
Timeline
≤ 6 months
The Problem

Desflurane has the highest global warming potential among anesthetic gases at 2500x more than carbon dioxide. Using just one bottle of desflurane is equivalent to burning 440kg of coal. Among other inhaled anesthetics, desflurane also has the lowest clinical potential, requiring higher concentrations to achieve the same effect.

The Solution

Remove desflurane from operating rooms. Safe, effective, and less-costly alternatives exist including sevoflurane or total intravenous anesthesia (TIVA).

Choosing Wisely Canada logo

This solution is featured by Choosing Wisely Canada

Don't use desflurane when other anesthetic drugs and techniques are equally effective and less harmful to the environment.

Anesthetic gases possess significant global warming potential (GWP) and contribute approximately 5% of the harmful greenhouse gas emissions of a typical hospital. However, not all anesthetic gases are equally harmful. The anesthetic gas desflurane has the highest GWP at twenty times more than that of sevoflurane. In addition, when both are delivered at equal fresh gas flows, desflurane has approximately 50 times the impact of sevoflurane due to its lower potency. Patient care can be provided safely and efficiently without desflurane; anesthetic alternatives such as sevoflurane, intravenous anesthesia or regional techniques should be considered, depending on clinical and geographical context. The restriction of the use of desflurane is supported by the Canadian Anesthesia Society, American Society of Anesthesiologists and World Federation of Societies of Anaesthesiologists. The elimination of desflurane is an effective change that aligns with the Choosing Wisely environmental practice recommendations.

Canadian Coalition for Green Health Care logo

This solution is featured by the Canadian Coalition for Green Health Care

Learn more about this solution in the Coalition's Green Health Care Guidebook.

Barriers
- Resistance to changing clinical practices
Lack of staff education
Concerns about patient safety
Clinician desire for autonomy
Enablers
- Anaesthetist-led educational initiatives
Theatre sustainability committees
Hospital leadership structures
International anaesthesiology society guidelines
Provincial health system partnerships
Co-Benefits
- Significant financial savings
Improved air quality
Enhanced staff engagement
Better environmental sustainability
Reduced drug procurement costs
Implementation Steps
Suggest a resource
References & Evidence
CASCADES' Anesthetic Gases Primer
Reference document
POWER Wellbeing: National Campaign to Phase-out Desflurane in Canada
Reference document
Transforming health care: Sustainability success stories from the operating room
Reference document
Suggest a resource
Toolkit
Greener Gases Toolkit
Tool / Resource
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