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Switching from IV to oral paracetamol cover image

Switching from IV to oral paracetamol

Photo: Centre for Sustainable Medicine, National University of Singapore, Singapore

MitigationScope 3🏥Anaesthesia
Needle NudgerNeedle Nudger (>0.5 tCO₂e or <1 tCO₂e per primary practice)
Climate Impact
80+ tCO₂e
Absolute GHG Reduction
🛢️ Equivalent to at least 183 barrels of oil per year for every 300-bed hospital
Financial Impact
ImplicationsLow Saving ($0-$25,000)
Savings$22,320 for 15,000 surgeries per year; an estimated 98.3% reduction of total direct costs.
ROIImmediate
Implementation Feasibility
Investment
Low
Team Size
Small but mighty
Timeline
≤ 6 months
The Problem

Paracetamol is used for pain management after surgery. Intravenous paracetamol has 12x the lifetime carbon emissions compared to the oral form.

The Solution

Utilizing oral paracetamol is safe and cost-saving. Reserve intravenous paracetamol for patients designated NPO or those that cannot tolerate oral intake. There is no difference in the safety or analgesic effect between oral and intravenous paracetamol.

Choosing Wisely Canada logo

This solution is featured by Choosing Wisely Canada

Don’t prescribe intravenous (IV) antibiotics for patients who can safely be treated with an oral option, given that IV antibiotics have a higher carbon footprint.

There is emerging evidence that conditions traditionally treated with prolonged courses of IV antibiotics, such as osteomyelitis or infective endocarditis, can safely be treated with PO antibiotics after a lead in period of IV therapy. Studies from the UK estimated that oral antibiotics have a carbon footprint up to 90% lower than the IV equivalent, depending on the antibiotic – a one-week course of oral ciprofloxacin is associated with 1.4kg CO2e (6.8km by car) of emissions versus 100.1kg CO2e (485.9km by car) for intravenous ciprofloxacin. The same group ran an early oral antimicrobial step-down project which saved 300,000 British pounds (or ~$450,000 CAD) annually. Among patients on IV antibiotics, early transition to oral antibiotics has the additional co-benefits of reducing hospital length of stay, length of treatment, nursing care needs, in addition to lowering carbon footprint. *All kgCO2e to km conversions in these recommendations are based on a carbon footprint conversion factor of 206gCO2e/km for the average Canadian vehicle in 2017. From: International Energy Agency. Fuel Economy in Major Car Markets: Technology and Policy Drivers 2005-2017. March 2019.

Suggest a resource
References & Evidence
British Journal of Anaesthesia: Reducing costs and carbon footprint for preoperative oral paracetamol: implementation of a standardised pathway
Reference document
British Journal of Anaesthesia: Environmental and financial impacts of perioperative paracetamol use: a multicentre international life-cycle assessment
Reference document
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